At this event, senior management of
The event will begin at
With the capacity to grow active killer cells as a biological cancer therapy, NantKwest’s NK cells have been designed to induce cell death against cancers and virally infected cells by multiple modes of action that include: Direct killing via innate recognition in which NK cells release toxic granules directly into the target (diseased) cell through cell-to-cell contact; Antibody-mediated killing using haNKs, which are NK cells engineered to incorporate a high binding affinity receptor that binds to an administered antibody, enhancing the cancer cell killing effect of that antibody; Chimeric Antigen Receptor directed killing using the taNK® platform, which includes NK cells engineered to incorporate chimeric antigen receptors (CARs) to target tumor-specific antigens found on the surface of cancer cells. All three modes of killing (innate, antibody-mediated, and Chimeric Antigen Receptor directed killing) using the t-haNK™ platform, which is an innovative combination of our haNK® and taNK® platforms in a single cell.
Our haNK®, taNK®, and t-haNK™ platforms have been designed to address certain limitations of T-cell therapies including the reduction of risk of serious “cytokine storms.” As an “off-the-shelf” therapy, NantKwest’s NK cells do not rely on a patient’s own often compromised immune system. In Phase 1 clinical trials in patients with late stage cancer, Nantkwest’s NK cells have been administered as an investigational outpatient infusion therapy without any reported severe side effects to date, even at doses of 10 billion cells.
By leveraging an integrated and extensive genomics and transcriptomics
discovery and development engine, together with a pipeline of multiple,
clinical-stage, immuno-oncology programs, we believe
This press release contains forward-looking statements within the
meaning of the Private Securities Litigation Reform Act of 1995.Forward-looking
statements include statements concerning or implying the Company will be
successful in improving the treatment of cancer.Risks and
uncertainties related to this endeavor include, but are not limited to,
Forward-looking statements are based on management's current expectations and are subject to various risks and uncertainties that could cause actual results to differ materially and adversely from those expressed or implied by such forward-looking statements. Accordingly, these forward-looking statements do not constitute guarantees of future performance, and you are cautioned not to place undue reliance on these forward-looking statements.
These and other risks regarding our business are described in detail
For additional information please contact either of the individuals below:
SVP, Innovation and Investor Relations